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Mechanistically, the pathway is relatively well-mapped: semaglutide reduces fasting insulin → lowers LH-mediated ovarian androgen secretion → increases SHBG, which binds and inactivates free testosterone → creates a more favorable hormonal environment in the follicle

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[S2] [S10] A stronger example of human hip research Mellor and colleagues randomised 204 people with clinically diagnosed and MRI-confirmed gluteal tendinopathy to education plus exercise, a corticosteroid intervention or a wait-and-see group